Analyzing Residual Solvents in Pharmaceutical Products Using GC Headspace
RS (Sigma Aldrich 40133-U) to a 100 mL flask, dilute to volume with water, and mix. Prepare standard solutions for Class 1, Class 2 mix A, and Class 2 mix B residual solvents directly into the headspace (HS) vial as described by the method: • Class 1
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Qualification of Headspace High Performance Septa by Headspace
Vial blank samples were prepared by capping the empty 20 mL headspace crimp top vials or screw top vials directly; no effort was made to purge the vials with an inert gas prior to capping. These vial blank samples were used for blank background and potential
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Measurement of 1,4-dioxane in surface water by
2014/2/25 · All samples were collected in duplicate, and 5 mL water were placed in a 10 mL headspace vial containing 2 g NaCl. 50 μL of 1,4- dioxane-d8 solution (1.0 mg/L in milli-Q water) as an internal standard was added in the sample as soon as possible, and then the
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Residual Monomers in Polymers by Multiple Headspace Extraction using the Aijiren Headspace
vials. Before sealing, the vials were purged with nitrogen. Pure monomers were purchased from Sigma-Aldrich. These were analyzed by full evaporation in 10-mL headspace vials as external standards. Typically, 0.1 µL of the pure monomer was injected directly
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Experimental Considerations in Headspace Gas Chromatography
Headspace sample vials typically come in 10-mL and 20-mL sizes. Often, the analytical chemist needs to analyze a very small amount of a residual solvent in a matrix, which raises the issue of